Here in the McDevitt lab we test the patient samples for the presence of various disease biomarkers.
These cellular samples could be in the form of blood, saliva, brush biopsies from the cheek or tongue.
The selection of biomarkers will vary depending upon the disease. The level of expression of the biomarkers will change according to the stage of the disease
All the cellular testing is done using the Lab-On-A-Chip platform
Following the assays, are the cytomorphometric assessments and the measurements of biomarker expression profiles.
The cytomorphometric assessments will focus on cell morphometric data, such as cell size, cell volume, nuclear size, and the nuclear/cytoplasmic ratio, whereas the biomarker expression assessments, which will use fluorescence immunostaining of both cell surface and intracellular tumor related antigens.